STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gyaRPutative phosphoglycerate dehydrogenase; Function Code: 1.6 Amino Acid Biosynthesis: Serine family. (336 aa)    
Predicted Functional Partners:
PF0024
Putative glycerate kinase; Function Code: 5.6 Central Intermediary Metabolism: Other.
 
 0.952
PF1419
Hypothetical protein; Catalyzes the dephosphorylation of 2-phosphoglycolate.
  
 
 0.918
PF0320
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
       0.572
PF1188
Pyruvate kinase; Function Code: 6.7 Energy Metabolism: Glycolysis; Belongs to the pyruvate kinase family.
  
 
 0.401
rpl4
LSU ribosomal protein L4P; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 
 0.401
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.