node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PF0097 | PF1963 | PF0097 | PF1963 | Bacteriochlorophyll synthase, 43 kDa subunit homolog; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | 4-hydroxybenzoate octaprenyltransferase, putative; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.969 |
PF0097 | carS | PF0097 | PF0398 | Bacteriochlorophyll synthase, 43 kDa subunit homolog; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.925 |
PF0169 | carS | PF0169 | PF0398 | Putative nucleolar protein III (nol1-nop2-sun family); Function Code: 4.2 Cellular Processes: Cell division; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.643 |
PF0399 | PF0400 | PF0399 | PF0400 | Member of s1p family of ribosomal proteins; Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | 0.781 |
PF0399 | PF0401 | PF0399 | PF0401 | Member of s1p family of ribosomal proteins; Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | Methyltransferase; Function Code: 16.0 Unknown. | 0.658 |
PF0399 | carS | PF0399 | PF0398 | Member of s1p family of ribosomal proteins; Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.790 |
PF0400 | PF0399 | PF0400 | PF0399 | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | Member of s1p family of ribosomal proteins; Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | 0.781 |
PF0400 | PF0401 | PF0400 | PF0401 | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | Methyltransferase; Function Code: 16.0 Unknown. | 0.673 |
PF0400 | carS | PF0400 | PF0398 | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.842 |
PF0401 | PF0399 | PF0401 | PF0399 | Methyltransferase; Function Code: 16.0 Unknown. | Member of s1p family of ribosomal proteins; Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | 0.658 |
PF0401 | PF0400 | PF0401 | PF0400 | Methyltransferase; Function Code: 16.0 Unknown. | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | 0.673 |
PF0401 | carS | PF0401 | PF0398 | Methyltransferase; Function Code: 16.0 Unknown. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.658 |
PF0462 | carS | PF0462 | PF0398 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Function Code: 7.1 Fatty Acid and Phospholipid Metabolism: General; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.542 |
PF0462 | tpiA | PF0462 | PF1920 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Function Code: 7.1 Fatty Acid and Phospholipid Metabolism: General; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.532 |
PF1963 | PF0097 | PF1963 | PF0097 | 4-hydroxybenzoate octaprenyltransferase, putative; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Bacteriochlorophyll synthase, 43 kDa subunit homolog; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | 0.969 |
PF1963 | carS | PF1963 | PF0398 | 4-hydroxybenzoate octaprenyltransferase, putative; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.988 |
carS | PF0097 | PF0398 | PF0097 | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | Bacteriochlorophyll synthase, 43 kDa subunit homolog; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | 0.925 |
carS | PF0169 | PF0398 | PF0169 | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | Putative nucleolar protein III (nol1-nop2-sun family); Function Code: 4.2 Cellular Processes: Cell division; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.643 |
carS | PF0399 | PF0398 | PF0399 | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | Member of s1p family of ribosomal proteins; Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | 0.790 |
carS | PF0400 | PF0398 | PF0400 | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | 0.842 |