STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF0444Hydrolase; Function Code: 16.0 Unknown. (364 aa)    
Predicted Functional Partners:
PF0443
Function Code: 14.4 Transport and Binding Proteins: Carbohydrates, organic alcohols, and acids.
 
     0.912
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Is very specific for its substrate, since it is not able to use D-glucose, D- fructose, D-mannose, 2-deoxy-D-glucose, and D-glucosamine as substrates; Belongs to the GHMP kinase family. GalK subfamily.
       0.849
PF1547
Endoglucanase; Function Code: 5.1 Central Intermediary Metabolism: Degradation of polysaccharides; (celM).
      
 0.790
PF0073
Beta-glucosidase; Function Code: 5.1 Central Intermediary Metabolism: Degradation of polysaccharides; Belongs to the glycosyl hydrolase 1 family.
     
 0.762
PF0442
Beta-glucosidase; Function Code: 5.1 Central Intermediary Metabolism: Degradation of polysaccharides; Belongs to the glycosyl hydrolase 1 family.
     
 0.751
PF0854
Function Code: 5.1 Central Intermediary Metabolism: Degradation of polysaccharides.
      
 0.751
PF0446
NDP-sugar synthase; Function Code: 3.2 Cell Envelope: Surface polysaccharides, lipopolysaccharides and antigens.
     
 0.670
PF0870
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
      
 0.670
PF1935
Amylopullulanase; Function Code: 5.1 Central Intermediary Metabolism: Degradation of polysaccharides.
 
   
 0.646
PF0953
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
  
     0.575
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.