STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
gorGlyceraldehyde-3-phosphate:ferredoxin oxidoreductase; Glycolytic enzyme that acts in the place of glyceraldehyde-3- phosphate dehydrogenase (GAPDH) and phosphoglycerate kinase (PGK). Plays a role in anabolic gluconeogenesis; Belongs to the AOR/FOR family. (653 aa)    
Predicted Functional Partners:
gap
Glyceraldehyde-3-phosphate dehydrogenase; Active in the presence of NAD and NADP; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
    
 0.977
pgk
Phosphoglycerate kinase; Function Code: 6.7 Energy Metabolism: Glycolysis; Belongs to the phosphoglycerate kinase family.
 
  
 0.948
fbp
Hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.935
PF0755
Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase; Function Code: 6.7 Energy Metabolism: Glycolysis; (NADP+); Belongs to the aldehyde dehydrogenase family.
   
 
 0.914
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
    
  0.911
fba
Possible 1,6-fructose biphosphate aldolase; Function Code: 6.7 Energy Metabolism: Glycolysis; Belongs to the DeoC/FbaB aldolase family.
     
 0.902
apgM
Phosphonopyruvate decarboxylase bcpc; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
  0.900
pgiA
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
  
  
  0.834
PF1688
Transketolase N-terminal section; Function Code: 6.8 Energy Metabolism: Pentose phosphate pathway.
  
  
  0.824
PF1689
Transketolase C-terminal section; Function Code: 6.8 Energy Metabolism: Pentose phosphate pathway.
  
  
  0.823
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.