STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mngBHypothetical protein; Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG). (242 aa)    
Predicted Functional Partners:
mngA
Hypothetical protein; Transfers a mannosyl group from GDP-mannose to phosphoglycerate to form mannosyl-3-phosphoglycerate (MPG). Belongs to the glycosyltransferase 2 family.
  
 0.999
PF0589
Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; Function Code: 3.2 Cell Envelope: Surface polysaccharides, lipopolysaccharides and antigens; (manC); Belongs to the mannose-6-phosphate isomerase type 2 family.
 
   
 0.943
PF1728
NDP-sugar synthase; Function Code: 3.2 Cell Envelope: Surface polysaccharides, lipopolysaccharides and antigens.
  
   
 0.679
PF0588
Phospho-sugar mutase; Function Code: 3.2 Cell Envelope: Surface polysaccharides, lipopolysaccharides and antigens.
       0.670
PF0868
NDP-sugar synthase; Function Code: 3.2 Cell Envelope: Surface polysaccharides, lipopolysaccharides and antigens.
  
   
 0.664
PF0592
ATP-dependent RNA helicase, putative; Function Code: 12.3 Transcription: RNA processing.
       0.642
PF0593
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical; Belongs to the UPF0282 family.
       0.642
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis.
 
     0.561
PF0596
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
       0.408
PF1916
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
 
     0.400
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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