STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF0670RNase l inhibitor; Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS. (590 aa)    
Predicted Functional Partners:
prf1
Peptide chain release factor eRF, subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
  
 
 0.994
rpl12
LSU ribosomal protein L12A; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.
  
   0.943
rps6e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps6E).
  
 
 0.920
rps3ae
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps3AE).
  
 
 0.911
rps3
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
  
 
 0.905
rps15
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps15P).
  
 
 0.903
rps24e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps24E).
 
   0.897
rps4e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps4E).
  
 
 0.895
rps12
SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
  
 
 0.892
rpl10
LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 
 0.884
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.