STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF0740Heavy-metal transporting cpx-type atpase; Function Code: 14.5 Transport and Binding Proteins: Cations. (799 aa)    
Predicted Functional Partners:
PF0739
Transcriptional regulatory protein, asnC family; Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS.
     
 0.971
PF0727
Function Code: 16.4 Hypothetical.
     
 0.918
PF0864
Transcriptional regulatory protein, asnC family; Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS.
     
 0.892
PF0741
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
   
 
 0.882
wtpA
Hypothetical protein; Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate, with a preference for tungstate.
     
 0.688
PF0851
Iron-dependent repressor; Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS.
     
 0.657
PF1457
Glutaredoxin/thioredoxin-like protein; Function Code: 6.4 Energy Metabolism: Electron transport.
 
 
 
 0.654
tgtA
Queuine trna-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
       0.643
PF0690
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
   
 
 0.579
PF0373
Putative ABC transporter, periplasmic binding protein; Function Code: 14.1 Transport and Binding Proteins: General.
     
 0.543
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.