STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF0857Function Code: 14.5 Transport and Binding Proteins: Cations. (663 aa)    
Predicted Functional Partners:
PF0858
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
 
  
 0.998
PF0723
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
     
 0.654
PF1194
Transcriptional regulator (furr family); Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS.
     
 0.649
PF1287
Putative ABC transporter (ATP-binding protein); Function Code: 14.1 Transport and Binding Proteins: General.
     
 0.643
PF0742
Putative ferritin homolog; Function Code: 14.6 Transport and Binding Proteins: Other; (rsgA).
     
 0.638
PF0859
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
       0.561
PF1373
Cation transporter, putative; Function Code: 14.5 Transport and Binding Proteins: Cations.
 
   
 0.545
PF0860
btpA family protein; Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS; Belongs to the BtpA family.
 
     0.496
nnrD
Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]
 
     0.460
PF1286
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
     
 0.453
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.