node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PF1266 | PF1858 | PF1266 | PF1858 | Cystathionine gamma-lyase (gamma-cystathionase); Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | Cysteine synthase; Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | 0.997 |
PF1266 | hydA | PF1266 | PF0894 | Cystathionine gamma-lyase (gamma-cystathionase); Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | Sulfhydrogenase alpha subunit; Part of a bifunctional enzyme complex that functions as an NADPH-dependent hydrogen-evolving hydrogenase with sulfur-reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity not exhibited with NAD. The alpha and delta subunits form the hydrogenase component that catalyzes the reduction of protons to evolve hydrogen. | 0.907 |
PF1266 | hydB | PF1266 | PF0891 | Cystathionine gamma-lyase (gamma-cystathionase); Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | Sulfhydrogenase beta subunit; Part of a bifunctional enzyme complex that functions as an NADPH-dependent hydrogen-evolving hydrogenase with sulfur reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity not exhibited with NAD. The beta and gamma subunits form the sulfur reducing component that catalyzes the cytoplasmic production of hydrogen sulfide in the presence of elemental sulfur. Not active in the presence of sodium sulfate, sodium sulfite, sodium thiosulfate or cysteine. | 0.900 |
PF1266 | hydD | PF1266 | PF0893 | Cystathionine gamma-lyase (gamma-cystathionase); Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | Sulfhydrogenase delta subunit; Part of a bifunctional enzyme complex that functions as an NADPH-dependent hydrogen-evolving hydrogenase with sulfur reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity not exhibited with NAD. The alpha and delta subunits form the hydrogenase component that catalyzes the reduction of protons to evolve hydrogen. | 0.900 |
PF1266 | hydG | PF1266 | PF0892 | Cystathionine gamma-lyase (gamma-cystathionase); Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | Sulfhydrogenase gamma subunit; Part of a bifunctional enzyme complex that functions as an NADPH-dependent hydrogen-evolving hydrogenase with sulfur reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity not exhibited with NAD. The beta and gamma subunits form the sulfur reducing component that catalyzes the cytoplasmic production of hydrogen sulfide in the presence of elemental sulfur. Not active in the presence of sodium sulfate, sodium sulfite, sodium thiosulfate or cysteine. | 0.904 |
PF1266 | shyA | PF1266 | PF1332 | Cystathionine gamma-lyase (gamma-cystathionase); Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | H-II alpha (hydrogenase subunit alpha); Part of a bifunctional enzyme complex that functions as a hydrogen-evolving hydrogenase with sulfur-reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity exhibited with NAD in addition to NADPH. The alpha and delta subunits form the hydrogenase component that catalyzes the reduction of protons to evolve hydrogen. | 0.907 |
PF1266 | shyB | PF1266 | PF1329 | Cystathionine gamma-lyase (gamma-cystathionase); Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | H-II hydrogenase subunit beta; Part of a bifunctional enzyme complex that functions as a hydrogen-evolving hydrogenase with sulfur-reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity exhibited with NAD in addition to NADPH. The beta and gamma subunits form the sulfur-reducing component that catalyzes the cytoplasmic production of hydrogen sulfide in the presence of elemental sulfur. | 0.900 |
PF1266 | shyC | PF1266 | PF1330 | Cystathionine gamma-lyase (gamma-cystathionase); Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | H-II gamma (hydrogenase subunit gamma); Part of a bifunctional enzyme complex that functions as a hydrogen-evolving hydrogenase with sulfur-reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity exhibited with NAD in addition to NADPH. The beta and gamma subunits form the sulfur-reducing component that catalyzes the cytoplasmic production of hydrogen sulfide in the presence of elemental sulfur. | 0.904 |
PF1266 | shyD | PF1266 | PF1331 | Cystathionine gamma-lyase (gamma-cystathionase); Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | H-II delta (hydrogenase subunit delta); Part of a bifunctional enzyme complex that functions as a hydrogen-evolving hydrogenase with sulfur-reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity exhibited with NAD in addition to NADPH. The alpha and delta subunits form the hydrogenase component that catalyzes the reduction of protons to evolve hydrogen. | 0.900 |
PF1858 | PF1266 | PF1858 | PF1266 | Cysteine synthase; Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | Cystathionine gamma-lyase (gamma-cystathionase); Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | 0.997 |
PF1858 | hydA | PF1858 | PF0894 | Cysteine synthase; Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | Sulfhydrogenase alpha subunit; Part of a bifunctional enzyme complex that functions as an NADPH-dependent hydrogen-evolving hydrogenase with sulfur-reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity not exhibited with NAD. The alpha and delta subunits form the hydrogenase component that catalyzes the reduction of protons to evolve hydrogen. | 0.904 |
PF1858 | hydB | PF1858 | PF0891 | Cysteine synthase; Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | Sulfhydrogenase beta subunit; Part of a bifunctional enzyme complex that functions as an NADPH-dependent hydrogen-evolving hydrogenase with sulfur reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity not exhibited with NAD. The beta and gamma subunits form the sulfur reducing component that catalyzes the cytoplasmic production of hydrogen sulfide in the presence of elemental sulfur. Not active in the presence of sodium sulfate, sodium sulfite, sodium thiosulfate or cysteine. | 0.900 |
PF1858 | hydD | PF1858 | PF0893 | Cysteine synthase; Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | Sulfhydrogenase delta subunit; Part of a bifunctional enzyme complex that functions as an NADPH-dependent hydrogen-evolving hydrogenase with sulfur reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity not exhibited with NAD. The alpha and delta subunits form the hydrogenase component that catalyzes the reduction of protons to evolve hydrogen. | 0.900 |
PF1858 | hydG | PF1858 | PF0892 | Cysteine synthase; Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | Sulfhydrogenase gamma subunit; Part of a bifunctional enzyme complex that functions as an NADPH-dependent hydrogen-evolving hydrogenase with sulfur reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity not exhibited with NAD. The beta and gamma subunits form the sulfur reducing component that catalyzes the cytoplasmic production of hydrogen sulfide in the presence of elemental sulfur. Not active in the presence of sodium sulfate, sodium sulfite, sodium thiosulfate or cysteine. | 0.905 |
PF1858 | shyA | PF1858 | PF1332 | Cysteine synthase; Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | H-II alpha (hydrogenase subunit alpha); Part of a bifunctional enzyme complex that functions as a hydrogen-evolving hydrogenase with sulfur-reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity exhibited with NAD in addition to NADPH. The alpha and delta subunits form the hydrogenase component that catalyzes the reduction of protons to evolve hydrogen. | 0.904 |
PF1858 | shyB | PF1858 | PF1329 | Cysteine synthase; Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | H-II hydrogenase subunit beta; Part of a bifunctional enzyme complex that functions as a hydrogen-evolving hydrogenase with sulfur-reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity exhibited with NAD in addition to NADPH. The beta and gamma subunits form the sulfur-reducing component that catalyzes the cytoplasmic production of hydrogen sulfide in the presence of elemental sulfur. | 0.900 |
PF1858 | shyC | PF1858 | PF1330 | Cysteine synthase; Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | H-II gamma (hydrogenase subunit gamma); Part of a bifunctional enzyme complex that functions as a hydrogen-evolving hydrogenase with sulfur-reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity exhibited with NAD in addition to NADPH. The beta and gamma subunits form the sulfur-reducing component that catalyzes the cytoplasmic production of hydrogen sulfide in the presence of elemental sulfur. | 0.905 |
PF1858 | shyD | PF1858 | PF1331 | Cysteine synthase; Function Code: 1.6 Amino Acid Biosynthesis: Serine family. | H-II delta (hydrogenase subunit delta); Part of a bifunctional enzyme complex that functions as a hydrogen-evolving hydrogenase with sulfur-reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity exhibited with NAD in addition to NADPH. The alpha and delta subunits form the hydrogenase component that catalyzes the reduction of protons to evolve hydrogen. | 0.900 |
frxA | hydA | PF0975 | PF0894 | frxA; Function Code: 6.4 Energy Metabolism: Electron transport. | Sulfhydrogenase alpha subunit; Part of a bifunctional enzyme complex that functions as an NADPH-dependent hydrogen-evolving hydrogenase with sulfur-reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity not exhibited with NAD. The alpha and delta subunits form the hydrogenase component that catalyzes the reduction of protons to evolve hydrogen. | 0.768 |
frxA | hydD | PF0975 | PF0893 | frxA; Function Code: 6.4 Energy Metabolism: Electron transport. | Sulfhydrogenase delta subunit; Part of a bifunctional enzyme complex that functions as an NADPH-dependent hydrogen-evolving hydrogenase with sulfur reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity not exhibited with NAD. The alpha and delta subunits form the hydrogenase component that catalyzes the reduction of protons to evolve hydrogen. | 0.593 |