STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
porAPyruvate ferredoxin oxidoreductase subunit alpha-2; Function Code: 6.5 Energy Metabolism: Fermentation. (396 aa)    
Predicted Functional Partners:
porB
Pyruvate ferredoxin oxidoreductase subunit beta-2; Function Code: 6.5 Energy Metabolism: Fermentation.
 0.999
porD
Pyruvate ferredoxin oxidoreductase subunit delta; Function Code: 6.5 Energy Metabolism: Fermentation.
 
 0.999
vorB
2-ketovalerate ferredoxin oxidoreductase subunit beta-2; Function Code: 6.5 Energy Metabolism: Fermentation.
 
 0.998
porG
Pyruvate ferredoxin oxidoreductase/2-ketovalerate ferredoxin oxidoreductase gamma subunit; Function Code: 6.5 Energy Metabolism: Fermentation.
 
 0.998
vorD
2-ketovalerate ferredoxin oxidoreductase subunit delta-2; Function Code: 6.5 Energy Metabolism: Fermentation.
 
 
 0.984
PF1772
2-keto acid:ferredoxin oxidoreductase subunit beta; Function Code: 6.5 Energy Metabolism: Fermentation.
 
 0.975
PF0753
2-keto acid:ferredoxin oxidoreductase subunit beta; Function Code: 6.5 Energy Metabolism: Fermentation.
  
 0.972
PF1769
2-keto acid:ferredoxin oxidoreductase subunit beta; Function Code: 6.5 Energy Metabolism: Fermentation.
  
 0.972
acdAI
Acetyl coenzyme A synthetase (ADP forming); Catalyzes the reversible formation of acetate and ATP from acetyl-CoA by using ADP and phosphate. Can use other substrates such as isobutyryl-CoA, propionyl-CoA and butyryl-CoA, but not indoleacetyl- CoA, phenylacetyl-CoA or succinyl-CoA. Seems to be involved primarily in the conversion of acetyl-CoA to acetate. Participates in the degradation of branched-chain amino acids via branched-chain-acyl-CoA esters; Belongs to the acetate CoA ligase alpha subunit family.
  
 0.953
PF0973
Acetyl CoA synthase; Function Code: 7.1 Fatty Acid and Phospholipid Metabolism: General; (acaB).
  
 
 0.939
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.