STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
frxAfrxA; Function Code: 6.4 Energy Metabolism: Electron transport. (137 aa)    
Predicted Functional Partners:
PF0972
Acyl carrier protein synthase; Function Code: 7.1 Fatty Acid and Phospholipid Metabolism: General; (acaA); Belongs to the thiolase-like superfamily. UPF0219 family.
     
 0.909
porG
Pyruvate ferredoxin oxidoreductase/2-ketovalerate ferredoxin oxidoreductase gamma subunit; Function Code: 6.5 Energy Metabolism: Fermentation.
     
 0.846
PF0549
Hydrogenase expression/formation protein; Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS; (hypD).
     
 0.786
PF0976
Putative transmembrane protein; Function Code: 16 Unknown:; (frxB).
       0.782
PF0977
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
       0.782
PF0978
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
       0.782
PF0604
Hydrogenase expression/formation protein; Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS; (hypE).
     
 0.778
hydA
Sulfhydrogenase alpha subunit; Part of a bifunctional enzyme complex that functions as an NADPH-dependent hydrogen-evolving hydrogenase with sulfur-reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity not exhibited with NAD. The alpha and delta subunits form the hydrogenase component that catalyzes the reduction of protons to evolve hydrogen.
 
 
 0.768
PF0617
Hydrogenase maturation protease; Function Code: 6.4 Energy Metabolism: Electron transport; (hycI).
      
 0.759
PF1401
Peptidyl-prolyl cis-trans isomerase; Function Code: 13.3 Translation: Protein modification; (slyD).
      
 0.751
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.