STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF1056Aspartate-semialdehyde dehydrogenase; Function Code: 1.3 Amino Acid Biosynthesis: Aspartate family. (334 aa)    
Predicted Functional Partners:
PF1052
Putative aspartokinase; Function Code: 1.3 Amino Acid Biosynthesis: Aspartate family.
 
 
 0.997
PF1053
Aspartokinase II alpha subunit; Function Code: 1.3 Amino Acid Biosynthesis: Aspartate family.
 
 
 0.997
PF1104
Homoserine dehydrogenase; Function Code: 1.3 Amino Acid Biosynthesis: Aspartate family.
 
 0.984
dapAL
Putative dihydrodipicolinate synthase; Function Code: 1.3 Amino Acid Biosynthesis: Aspartate family; (dapA); Belongs to the DapA family.
 
 
 0.981
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
  
 0.957
PF1055
Threonine synthase (pyridoxal phosphate binding); Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
 0.877
pgk
Phosphoglycerate kinase; Function Code: 6.7 Energy Metabolism: Glycolysis; Belongs to the phosphoglycerate kinase family.
  
 
 0.812
argG
Argininosuccinate synthase; Function Code: 1.4 Amino Acid Biosynthesis: Glutamate family; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
  
 0.802
PF1266
Cystathionine gamma-lyase (gamma-cystathionase); Function Code: 1.6 Amino Acid Biosynthesis: Serine family.
  
  
 0.761
PF0940
3-isopropylmalate dehydrogenase 2; Function Code: 1.5 Amino Acid Biosynthesis: Pyruvate family (leuB2); (leuB).
  
  
 0.691
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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