node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PF0254 | PF0366 | PF0254 | PF0366 | Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | 0.929 |
PF0254 | coaD | PF0254 | PF1084 | Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. | 0.940 |
PF0366 | PF0254 | PF0366 | PF0254 | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.929 |
PF0366 | coaD | PF0366 | PF1084 | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. | 0.914 |
PF0449 | coaD | PF0449 | PF1084 | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. | 0.473 |
PF1083 | PF1085 | PF1083 | PF1085 | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | 0.596 |
PF1083 | coaD | PF1083 | PF1084 | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. | 0.799 |
PF1085 | PF1083 | PF1085 | PF1083 | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | 0.596 |
PF1085 | coaD | PF1085 | PF1084 | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. | 0.594 |
PF1087 | coaD | PF1087 | PF1084 | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical; Belongs to the PDCD5 family. | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. | 0.475 |
PF1087 | rpl10e | PF1087 | PF1279 | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical; Belongs to the PDCD5 family. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | 0.607 |
PF1440 | coaD | PF1440 | PF1084 | Dna/pantothenate metabolism flavoprotein (dfp); Function Code: 11.1 Replication: DNA replication, restriction, modification, recombination, and repair. | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. | 0.912 |
coaD | PF0254 | PF1084 | PF0254 | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. | Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.940 |
coaD | PF0366 | PF1084 | PF0366 | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | 0.914 |
coaD | PF0449 | PF1084 | PF0449 | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | 0.473 |
coaD | PF1083 | PF1084 | PF1083 | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | 0.799 |
coaD | PF1085 | PF1084 | PF1085 | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | 0.594 |
coaD | PF1087 | PF1084 | PF1087 | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical; Belongs to the PDCD5 family. | 0.475 |
coaD | PF1440 | PF1084 | PF1440 | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. | Dna/pantothenate metabolism flavoprotein (dfp); Function Code: 11.1 Replication: DNA replication, restriction, modification, recombination, and repair. | 0.912 |
coaD | kae1 | PF1084 | PF0172 | Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.490 |