STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rubRubredoxin; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. (54 aa)    
Predicted Functional Partners:
sorA
Superoxide reductase; Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide; Belongs to the desulfoferrodoxin family.
  
  
 0.993
PF1283
Rubrerythrin; Function Code: 6.4 Energy Metabolism: Electron transport.
  
  
 0.968
PF1952
Iron-sulfur protein; Function Code: 6.4 Energy Metabolism: Electron transport.
     
 0.793
PF0610
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
      
 0.739
PF1033
Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.720
PF0742
Putative ferritin homolog; Function Code: 14.6 Transport and Binding Proteins: Other; (rsgA).
  
  
 0.649
PF1194
Transcriptional regulator (furr family); Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS.
  
  
 0.626
fdxA
Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
  
  
 0.616
PF0751
Flavoprotein; Function Code: 6.4 Energy Metabolism: Electron transport.
 
  
 0.580
PF0548
Hydrogenase expression/formation protein; Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS; (hypC).
  
  
 0.540
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.