node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PF1333 | PF1336 | PF1333 | PF1336 | Phosphomethylpyrimidine kinase (hmp-phosphate kinase); Function Code: 2.8 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Thiamine. | Cytosine permease; Function Code: 14.6 Transport and Binding Proteins: Other. | 0.928 |
PF1333 | PF1337 | PF1333 | PF1337 | Phosphomethylpyrimidine kinase (hmp-phosphate kinase); Function Code: 2.8 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Thiamine. | Transcriptional activator, putative; Function Code: 10 Regulatory Functions: REGULATORY FUNCTION. | 0.995 |
PF1333 | PF1338 | PF1333 | PF1338 | Phosphomethylpyrimidine kinase (hmp-phosphate kinase); Function Code: 2.8 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Thiamine. | Transcriptional activator, putative; Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS. | 0.999 |
PF1333 | PF1339 | PF1333 | PF1339 | Phosphomethylpyrimidine kinase (hmp-phosphate kinase); Function Code: 2.8 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Thiamine. | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | 0.544 |
PF1333 | PF1340 | PF1333 | PF1340 | Phosphomethylpyrimidine kinase (hmp-phosphate kinase); Function Code: 2.8 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Thiamine. | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | 0.538 |
PF1333 | PF1482 | PF1333 | PF1482 | Phosphomethylpyrimidine kinase (hmp-phosphate kinase); Function Code: 2.8 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Thiamine. | Function Code: 16.4 Hypothetical. | 0.690 |
PF1333 | samp2 | PF1333 | PF1061 | Phosphomethylpyrimidine kinase (hmp-phosphate kinase); Function Code: 2.8 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Thiamine. | Hypothetical protein; Functions as a protein modifier covalently attached to lysine residues of substrate proteins, as well as a sulfur carrier in tRNA thiolation. The protein modification process is termed sampylation and involves the formation of an isopeptide bond between the SAMP2 C- terminal glycine carboxylate and the epsilon-amino group of lysine residues on target proteins. Is able to form polymeric chains with itself likely at Lys-55, similar to ubiquitin and other ubiquitin-like proteins. May serve as a proteolytic signal in the cell to target proteins for degradation by prot [...] | 0.690 |
PF1333 | thiC | PF1333 | PF1531 | Phosphomethylpyrimidine kinase (hmp-phosphate kinase); Function Code: 2.8 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Thiamine. | Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.997 |
PF1333 | thiE | PF1333 | PF1334 | Phosphomethylpyrimidine kinase (hmp-phosphate kinase); Function Code: 2.8 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Thiamine. | Thiamine phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
PF1333 | thiM | PF1333 | PF1335 | Phosphomethylpyrimidine kinase (hmp-phosphate kinase); Function Code: 2.8 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Thiamine. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.999 |
PF1336 | PF1333 | PF1336 | PF1333 | Cytosine permease; Function Code: 14.6 Transport and Binding Proteins: Other. | Phosphomethylpyrimidine kinase (hmp-phosphate kinase); Function Code: 2.8 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Thiamine. | 0.928 |
PF1336 | PF1337 | PF1336 | PF1337 | Cytosine permease; Function Code: 14.6 Transport and Binding Proteins: Other. | Transcriptional activator, putative; Function Code: 10 Regulatory Functions: REGULATORY FUNCTION. | 0.790 |
PF1336 | PF1338 | PF1336 | PF1338 | Cytosine permease; Function Code: 14.6 Transport and Binding Proteins: Other. | Transcriptional activator, putative; Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS. | 0.790 |
PF1336 | PF1339 | PF1336 | PF1339 | Cytosine permease; Function Code: 14.6 Transport and Binding Proteins: Other. | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | 0.544 |
PF1336 | PF1340 | PF1336 | PF1340 | Cytosine permease; Function Code: 14.6 Transport and Binding Proteins: Other. | Hypothetical protein; Function Code: 16.1 Conserved Hypothetical. | 0.538 |
PF1336 | thiE | PF1336 | PF1334 | Cytosine permease; Function Code: 14.6 Transport and Binding Proteins: Other. | Thiamine phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.913 |
PF1336 | thiM | PF1336 | PF1335 | Cytosine permease; Function Code: 14.6 Transport and Binding Proteins: Other. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.927 |
PF1337 | PF1333 | PF1337 | PF1333 | Transcriptional activator, putative; Function Code: 10 Regulatory Functions: REGULATORY FUNCTION. | Phosphomethylpyrimidine kinase (hmp-phosphate kinase); Function Code: 2.8 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Thiamine. | 0.995 |
PF1337 | PF1336 | PF1337 | PF1336 | Transcriptional activator, putative; Function Code: 10 Regulatory Functions: REGULATORY FUNCTION. | Cytosine permease; Function Code: 14.6 Transport and Binding Proteins: Other. | 0.790 |
PF1337 | PF1338 | PF1337 | PF1338 | Transcriptional activator, putative; Function Code: 10 Regulatory Functions: REGULATORY FUNCTION. | Transcriptional activator, putative; Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS. | 0.981 |