STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trmYHypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (202 aa)    
Predicted Functional Partners:
PF0315
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
  
   
 0.883
pus10
Hypothetical protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. Belongs to the pseudouridine synthase Pus10 family.
 
   
 0.854
nep1
Hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
     
 0.833
PF0273
N-type ATP pyrophosphatase superfamily; Function Code: 16.0 Unknown.
  
   
 0.767
PF1402
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
       0.756
PF1401
Peptidyl-prolyl cis-trans isomerase; Function Code: 13.3 Translation: Protein modification; (slyD).
       0.649
PF2033
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
  
     0.607
PF1851
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
  
     0.592
PF1927
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
  
     0.576
PF0041
Putative oxidative cyclase; Function Code: 16.0 Unknown.
  
     0.572
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.