STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prf1Peptide chain release factor eRF, subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (420 aa)    
Predicted Functional Partners:
PF0670
RNase l inhibitor; Function Code: 10 Regulatory Functions: REGULATORY FUNCTIONS.
  
 
 0.994
rpl15e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl15E).
  
 0.890
tuf
Translation elongation factor eF-1, subunit alpha (tuf); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
  
 0.875
eif2b
Translation initiation factor eIF-2, subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
  
  
 0.855
PF1673
Protoporphyrinogen oxidase; Function Code: 2.3 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Heme and porphyrin; (hemK).
   
 0.851
rpl30
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl30P).
  
 0.841
rps15
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps15P).
 
 0.832
rps4e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps4E).
  
  0.826
eif2g
Translation initiation factor eIF-2, subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
  
  
 0.820
rpl24
LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
  
  0.818
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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