node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PF0364 | nep1 | PF0364 | PF1262 | Tyrosine-protein kinase; Function Code: 10.0 Regulatory functions: regulatory functions. | Hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.410 |
PF0364 | rps24e | PF0364 | PF0253 | Tyrosine-protein kinase; Function Code: 10.0 Regulatory functions: regulatory functions. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps24E). | 0.832 |
PF0364 | rps4 | PF0364 | PF1649 | Tyrosine-protein kinase; Function Code: 10.0 Regulatory functions: regulatory functions. | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.999 |
PF0364 | rps6e | PF0364 | PF0488 | Tyrosine-protein kinase; Function Code: 10.0 Regulatory functions: regulatory functions. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps6E). | 0.999 |
PF0364 | vapC | PF0364 | PF1205 | Tyrosine-protein kinase; Function Code: 10.0 Regulatory functions: regulatory functions. | Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. | 0.999 |
flpA | infB | PF0059 | PF1137 | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity). | 0.701 |
flpA | nep1 | PF0059 | PF1262 | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | Hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.999 |
flpA | rpl10e | PF0059 | PF1279 | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | 0.887 |
flpA | rpl21e | PF0059 | PF1035 | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl21E). | 0.583 |
flpA | rpl31e | PF0059 | PF0378 | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl31E). | 0.579 |
flpA | rps24e | PF0059 | PF0253 | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps24E). | 0.412 |
flpA | rps4 | PF0059 | PF1649 | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.999 |
flpA | rps6e | PF0059 | PF0488 | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps6E). | 0.999 |
flpA | vapC | PF0059 | PF1205 | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. | 0.463 |
infB | flpA | PF1137 | PF0059 | Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity). | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | 0.701 |
infB | rpl10e | PF1137 | PF1279 | Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity). | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | 0.994 |
infB | rpl21e | PF1137 | PF1035 | Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity). | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl21E). | 0.847 |
infB | rpl31e | PF1137 | PF0378 | Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity). | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl31E). | 0.838 |
infB | rps24e | PF1137 | PF0253 | Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity). | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps24E). | 0.992 |
infB | rps4 | PF1137 | PF1649 | Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity). | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.999 |