node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PF1678 | PF1682 | PF1678 | PF1682 | 2-isopropylmalate synthase; Function Code: 1.5 Amino Acid Biosynthesis: Pyruvate family; (leuA). | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | 0.510 |
PF1678 | argG | PF1678 | PF0207 | 2-isopropylmalate synthase; Function Code: 1.5 Amino Acid Biosynthesis: Pyruvate family; (leuA). | Argininosuccinate synthase; Function Code: 1.4 Amino Acid Biosynthesis: Glutamate family; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.491 |
PF1678 | leuC2 | PF1678 | PF1679 | 2-isopropylmalate synthase; Function Code: 1.5 Amino Acid Biosynthesis: Pyruvate family; (leuA). | Putative 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.996 |
PF1678 | leuD2 | PF1678 | PF1680 | 2-isopropylmalate synthase; Function Code: 1.5 Amino Acid Biosynthesis: Pyruvate family; (leuA). | Putative 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.996 |
PF1678 | lysJ | PF1678 | PF1685 | 2-isopropylmalate synthase; Function Code: 1.5 Amino Acid Biosynthesis: Pyruvate family; (leuA). | Acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. | 0.777 |
PF1678 | lysK | PF1678 | PF1686 | 2-isopropylmalate synthase; Function Code: 1.5 Amino Acid Biosynthesis: Pyruvate family; (leuA). | Acetylornithine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. | 0.769 |
PF1678 | lysY | PF1678 | PF1683 | 2-isopropylmalate synthase; Function Code: 1.5 Amino Acid Biosynthesis: Pyruvate family; (leuA). | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | 0.811 |
PF1678 | lysZ | PF1678 | PF1684 | 2-isopropylmalate synthase; Function Code: 1.5 Amino Acid Biosynthesis: Pyruvate family; (leuA). | Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. | 0.669 |
PF1682 | PF1678 | PF1682 | PF1678 | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | 2-isopropylmalate synthase; Function Code: 1.5 Amino Acid Biosynthesis: Pyruvate family; (leuA). | 0.510 |
PF1682 | leuC2 | PF1682 | PF1679 | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | Putative 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.431 |
PF1682 | leuD2 | PF1682 | PF1680 | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | Putative 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.523 |
PF1682 | lysJ | PF1682 | PF1685 | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | Acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. | 0.799 |
PF1682 | lysK | PF1682 | PF1686 | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | Acetylornithine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. | 0.928 |
PF1682 | lysY | PF1682 | PF1683 | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | 0.881 |
PF1682 | lysZ | PF1682 | PF1684 | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. | 0.989 |
argF | argG | PF0594 | PF0207 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis. | Argininosuccinate synthase; Function Code: 1.4 Amino Acid Biosynthesis: Glutamate family; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.997 |
argF | argH | PF0594 | PF0208 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis. | Argininosuccinate lyase; Function Code: 1.4 Amino Acid Biosynthesis: Glutamate family. | 0.819 |
argF | lysJ | PF0594 | PF1685 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis. | Acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. | 0.868 |
argF | lysK | PF0594 | PF1686 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis. | Acetylornithine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. | 0.943 |
argF | lysY | PF0594 | PF1683 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis. | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. | 0.968 |