STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF1783Function Code: 2.5 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Molybdopterin; (moeA-2). (395 aa)    
Predicted Functional Partners:
moaB
Molybdenum cofactor biosynthesis protein; Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor; Belongs to the MoaB/Mog family.
 
 0.983
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
 
 0.962
PF0542
Function Code: 2.5 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Molybdopterin; (moeA-1).
  
  
 
0.908
moaC
Molybdenum cofactor biosynthesis protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
  
 0.871
moaA
Molybdenum cofactor biosynthesis protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
 0.852
PF1782
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
       0.782
PF0100
Molybdopterin converting factor (subunit 2); Function Code: 2.5 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Molybdopterin.
 
  
 0.771
PF1954
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
 
 
 0.680
pfkC
ADP-dependent phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. As a phosphoryl group donor, ADP can be replaced by GDP, ATP, and GTP to a limited extent; Belongs to the carbohydrate kinase PfkC family.
       0.657
PF0345
Molybdopterin converting factor, subunit 1; Function Code: 2.5 Biosynthesis Of Cofactors, Prosthetic Groups And Carriers: Molybdopterin; (moaD).
  
  
 0.587
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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