node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PF0364 | eif2a | PF0364 | PF1140 | Tyrosine-protein kinase; Function Code: 10.0 Regulatory functions: regulatory functions. | Translation initiation factor eIF-2, subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | 0.766 |
PF0364 | nep1 | PF0364 | PF1262 | Tyrosine-protein kinase; Function Code: 10.0 Regulatory functions: regulatory functions. | Hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.410 |
PF0364 | rpl15e | PF0364 | PF0876 | Tyrosine-protein kinase; Function Code: 10.0 Regulatory functions: regulatory functions. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl15E). | 0.517 |
PF0364 | rps24e | PF0364 | PF0253 | Tyrosine-protein kinase; Function Code: 10.0 Regulatory functions: regulatory functions. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps24E). | 0.832 |
PF0364 | rps5 | PF0364 | PF1804 | Tyrosine-protein kinase; Function Code: 10.0 Regulatory functions: regulatory functions. | SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. | 0.999 |
PF0364 | rps6e | PF0364 | PF0488 | Tyrosine-protein kinase; Function Code: 10.0 Regulatory functions: regulatory functions. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps6E). | 0.999 |
PF0364 | vapC | PF0364 | PF1205 | Tyrosine-protein kinase; Function Code: 10.0 Regulatory functions: regulatory functions. | Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. | 0.999 |
eif2a | PF0364 | PF1140 | PF0364 | Translation initiation factor eIF-2, subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | Tyrosine-protein kinase; Function Code: 10.0 Regulatory functions: regulatory functions. | 0.766 |
eif2a | flpA | PF1140 | PF0059 | Translation initiation factor eIF-2, subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | 0.679 |
eif2a | rpl10e | PF1140 | PF1279 | Translation initiation factor eIF-2, subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | 0.560 |
eif2a | rpl15e | PF1140 | PF0876 | Translation initiation factor eIF-2, subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl15E). | 0.686 |
eif2a | rps24e | PF1140 | PF0253 | Translation initiation factor eIF-2, subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps24E). | 0.999 |
eif2a | rps5 | PF1140 | PF1804 | Translation initiation factor eIF-2, subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. | 0.999 |
eif2a | rps6e | PF1140 | PF0488 | Translation initiation factor eIF-2, subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps6E). | 0.999 |
eif2a | vapC | PF1140 | PF1205 | Translation initiation factor eIF-2, subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. | 0.494 |
flpA | eif2a | PF0059 | PF1140 | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | Translation initiation factor eIF-2, subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. | 0.679 |
flpA | nep1 | PF0059 | PF1262 | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | Hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.999 |
flpA | rpl10e | PF0059 | PF1279 | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification. | 0.887 |
flpA | rpl14e | PF0059 | PF0819 | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl14E). | 0.702 |
flpA | rpl15e | PF0059 | PF0876 | Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. | Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl15E). | 0.699 |