STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpl35aeFunction Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl35AE). (87 aa)    
Predicted Functional Partners:
rpl44e
LSU ribosomal protein L44E; Binds to the 23S rRNA.
   
 0.999
rps24e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps24E).
   
 
 0.999
rpl18a
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rplXA).
  
 0.999
rpl31e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl31E).
   
 0.999
rps6e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps6E).
  
 
 0.999
rpl14e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl14E).
  
 0.999
rpl34e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl34E).
  
 0.999
rpl15e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl15E).
  
 0.999
rpl21e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rpl21E).
  
 0.999
rpl7ae
LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. Component of the 70S ribosome. Component of a box C/D small ribonucleoprotein (sRNP) particle that is involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site- specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic d [...]
   
 0.999
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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