STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
albAHypothetical protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (93 aa)    
Predicted Functional Partners:
PF1831
Archaeal histone a1; Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation (in vitro).
  
   
 0.867
rpl18a
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rplXA).
  
   
 0.855
rps24e
Function Code: 13.4 Translation: Ribosomal proteins: synthesis and modification; (rps24E).
      
 0.682
PF1542
Small nuclear ribonucleoprotein, putative; Function Code: 12.3 Transcription: RNA processing; Belongs to the snRNP Sm proteins family.
  
   
 0.658
adkA
Adenylate kinase (ATP-AMP transphosphorylase); Function Code: 9.2 Purines, Pyrimidines, Nucleosides and Nucleotides: Nucleotide and nucleoside interconversions; Belongs to the archaeal adenylate kinase family.
  
     0.614
radB
Recombinase; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.
      
 0.613
PF1862
DNA-binding protein; Function Code: 11.1 Replication: DNA replication, restriction, modification, recombination and repair.
  
     0.613
PF0239
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical; Belongs to the UPF0147 family.
  
     0.561
PF1882
Cell division control protein 48, aaa family; Function Code: 4.2 Cellular Processes: Cell division; (cdc48-2).
       0.533
PF0512
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
 
     0.500
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
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