STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mlg_0516Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: mca:MCA0373 phosphoribosylaminoimidazole synthetase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. (347 aa)    
Predicted Functional Partners:
Mlg_0515
Phosphoribosylglycinamide formyltransferase; KEGG: pae:PA0944 phosphoribosylaminoimidazole synthetase; TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein.
  
 0.999
Mlg_2474
KEGG: mca:MCA0673 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein.
  
 
 0.999
Mlg_0612
KEGG: vch:VC0275 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase.
  
 0.998
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.997
Mlg_2236
5-(carboxyamino)imidazole ribonucleotide synthase; KEGG: tbd:Tbd_2662 phosphoribosylaminoimidazole carboxylase, ATPase subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, ATPase subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp.
 
 
 0.995
Mlg_2237
5-(carboxyamino)imidazole ribonucleotide mutase; KEGG: eba:ebA116 phosphoribosylaminoimidazole carboxylase catalytic subunit (AIR carboxylase) (AIRC), gene: PurE or BSU06420; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase.
 
  
 0.982
Mlg_0611
KEGG: tcx:Tcr_0439 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme; MGS domain protein.
 
  
 0.981
Mlg_2257
KEGG: mca:MCA0021 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase.
 
  
 0.971
Mlg_1358
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; KEGG: pae:PA2629 adenylosuccinate lyase.
  
 
 0.926
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
  
 0.915
Your Current Organism:
Alkalilimnicola ehrlichii
NCBI taxonomy Id: 187272
Other names: A. ehrlichii MLHE-1, Alkalilimnicola ehrlichii MLHE-1, Alkalilimnicola ehrlichii str. MLHE-1, Alkalilimnicola ehrlichii strain MLHE-1, Mono Lake Gammaproteobacter MLHE-1, arsenite-oxidizing bacterium MLHE-1, gamma proteobacterium MLHE-1
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