STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mlg_2613PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mfa:Mfla_0256 phosphoribosyl-ATP pyrophosphohydrolase. (109 aa)    
Predicted Functional Partners:
Mlg_1201
PFAM: phosphoribosyl-AMP cyclohydrolase; KEGG: csa:Csal_1883 phosphoribosyl-AMP cyclohydrolase.
 
 0.999
hisG
ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
 
 
 0.998
Mlg_2615
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis; KEGG: sde:Sde_0489 response regulator receiver domain protein (CheY-like).
 
  
 0.996
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
 
  
 0.995
Mlg_2617
PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: pfo:Pfl_0323 imidazoleglycerol-phosphate dehydratase.
 
  
 0.994
Mlg_0577
PFAM: tRNA synthetase, class II (G, H, P and S); KEGG: mca:MCA1979 ATP phosphoribosyltransferase regulatory subunit.
 
 
 0.992
Mlg_2616
TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: glutamine amidotransferase class-I; KEGG: ppu:PP0290 glutamine amidotransferase HisH.
 
  
 0.992
Mlg_2215
PFAM: histidinol dehydrogenase; KEGG: mfa:Mfla_0248 histidinol dehydrogenase.
 
  
 0.976
Mlg_2612
TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: hch:HCH_01076 sec-independent protein secretion pathway components.
 
    0.898
Mlg_2214
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; KEGG: noc:Noc_2777 histidinol-phosphate aminotransferase.
 
  
 0.809
Your Current Organism:
Alkalilimnicola ehrlichii
NCBI taxonomy Id: 187272
Other names: A. ehrlichii MLHE-1, Alkalilimnicola ehrlichii MLHE-1, Alkalilimnicola ehrlichii str. MLHE-1, Alkalilimnicola ehrlichii strain MLHE-1, Mono Lake Gammaproteobacter MLHE-1, arsenite-oxidizing bacterium MLHE-1, gamma proteobacterium MLHE-1
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