STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mlg_2649Formamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase; KEGG: mca:MCA3072 formamidopyrimidine-DNA glycosylase; TIGRFAM: formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase. (277 aa)    
Predicted Functional Partners:
Mlg_2860
KEGG: mca:MCA2573 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2.
  
  
 0.985
Mlg_2082
KEGG: sgl:SG0461 dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase.
 
  
 0.980
Mlg_2647
KEGG: mca:MCA3076 hypothetical protein.
       0.745
Mlg_2648
KEGG: noc:Noc_2647 hypothetical protein.
       0.745
Mlg_2646
KEGG: noc:Noc_2645 ABC transporter, permease protein, putative.
       0.728
Mlg_2645
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mca:MCA3078 ABC transporter, ATP-binding protein.
       0.699
nth
DNA-(apurinic or apyrimidinic site) lyase / endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
   
  
 0.698
Mlg_1362
KEGG: mca:MCA1681 excinuclease ABC, C subunit; TIGRFAM: excinuclease ABC, C subunit; PFAM: Excinuclease ABC, C subunit domain protein; helix-hairpin-helix motif; excinuclease ABC, C subunit domain protein; UvrB/UvrC protein; SMART: Helix-hairpin-helix DNA-binding, class 1.
  
  
 0.681
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.544
Mlg_2763
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: hch:HCH_05965 glutamate synthase domain 2.
      
 0.515
Your Current Organism:
Alkalilimnicola ehrlichii
NCBI taxonomy Id: 187272
Other names: A. ehrlichii MLHE-1, Alkalilimnicola ehrlichii MLHE-1, Alkalilimnicola ehrlichii str. MLHE-1, Alkalilimnicola ehrlichii strain MLHE-1, Mono Lake Gammaproteobacter MLHE-1, arsenite-oxidizing bacterium MLHE-1, gamma proteobacterium MLHE-1
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