STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_1771Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g332844, p()=0.35, pid=19%. (53 aa)    
Predicted Functional Partners:
MTH_1770
Function Code:10.09 - Metabolism of Macromolecules, DNA replication--modification--repair--and recombination; similar to, sp:LN:C21H_HUMAN AC:P33991, p()=4.2E-104, pid=38%; Belongs to the MCM family.
       0.678
eif2b
Translation initiation factor eIF-2, beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-beta/eIF-5 family.
       0.577
MTH_1772
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:VCAP_BPT7 AC:P03716, p()=0.3, pid=13%.
       0.572
MTH_1766
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:RUVB_HAEIN AC:P44631, p()=0.87, pid=19%.
       0.522
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
       0.522
MTH_1768
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:H64505 AC:H64505, p()=1.4E-41, pid=30%.
       0.522
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.