STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_1791Glucose-1-phosphate thymidylyltransferase; Function Code:4.03 - Nucleotide Metabolism, Nucleotide sugars metabolism; similar to, sp:LN:RFBA_YEREN AC:P55257, p()=7.3E-102, pid=64%. (292 aa)    
Predicted Functional Partners:
MTH_1789
dTDP-glucose 4,6-dehydratase; Function Code:1.05 - Carbohydrate Metabolism, Fructose and mannose metabolism; similar to, gp:GI:g1666507 LN:LIU61226, p()=7.5E-100, pid=56%.
 
 0.995
MTH_1792
dTDP-4-dehydrorhamnose reductase; Function Code:1.05 - Carbohydrate Metabolism, Fructose and mannose metabolism; similar to, gp:GI:g1881547 LN:SPU09239, p()=8.7E-51, pid=39%.
 
  
 0.987
rmlC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
 
  
 0.981
eif2a
Translation initiation factor eIF-2, alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
   
 0.944
MTH_1185
Translation elongation factor, EF-1 alpha related protein; Function Code:10.08 - Metabolism of Macromolecules, Protein translation and modification; similar to, gp:GI:g1916927 LN:MMU87965, p()=1.1E-68, pid=30%.
   
 0.911
eif2g
Translation initiation factor eIF-2, gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
   
 0.911
eif2b
Translation initiation factor eIF-2, beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-beta/eIF-5 family.
  
 
 0.651
MTH_572
Polysaccharide biosynthesis protein; Function Code:11.02 - Cell envelope, Surface polysaccharides and lipopolysaccharides; similar to, sp:LN:SPSK_BACSU AC:P39631, p()=1.5E-16, pid=34%.
  
  
 0.634
MTH_573
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:SPSK_BACSU AC:P39631, p()=0.052, pid=18%.
  
  
 0.634
MTH_380
UDP-glucose 4-epimerase homolog; Function Code:4.03 - Nucleotide Metabolism, Nucleotide sugars metabolism; similar to, gp:GI:g1143204 LN:SSU34305, p()=3.5E-54, pid=71%.
 
 
 0.612
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.