STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_835Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:G64401 AC:G64401, p()=5.4E-19, pid=38%. (324 aa)    
Predicted Functional Partners:
MTH_834
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:H64404 AC:H64404, p()=5.9E-61, pid=40%.
 
  
 0.997
mfnA
Glutamate decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
    
 0.925
MTH_1698
Delta 1-pyrroline-5-carboxylate synthetase; Function Code:5.09 - L-Amino Acid Metabolism, Arginine and proline metabolism; similar to, pir:LN:B64357 AC:B64357, p()=9.6E-29, pid=34%.
 
   
 0.871
MTH_837
UDP-N-acetylglucosamine 2-epimerase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, pir:LN:G64487 AC:G64487, p()=3.2E-85, pid=38%.
       0.803
MTH_1557
Tungsten formylmethanofuran dehydrogenase, subunit A; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:S57456 AC:S57456, p()=0, pid=94%.
 
   
 0.801
mfnB
Conserved protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
 
   
 0.790
MTH_836
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, gp:GI:g1773354 LN:SAU81973, p()=6.7E-76, pid=38%; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
       0.781
MTH_838
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g165529, p()=0.0002, pid=07%.
       0.772
MTH_839
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:e290997:g1781137, p()=0.9995, pid=09%.
       0.772
MTH_1741
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y107_METJA AC:Q57571, p()=1.5E-108, pid=44%.
  
   
 0.739
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.