STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPHA2Ephrin type-A receptor 2. (328 aa)    
Predicted Functional Partners:
EFNA5
Ephrin-A5; Belongs to the ephrin family.
   
 0.938
GRB2
Growth factor receptor-bound protein 2.
   
 0.937
DDR2
Discoidin domain-containing receptor 2.
 
  
   0.822
EFNB2
Ephrin-B2; Belongs to the ephrin family.
   
 0.743
IGF1
Insulin-like growth factor I.
    
 0.719
Z169_10591
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.716
NTF3
Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family.
    
 0.711
BDNF
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
    
 0.700
PDGFC
Platelet-derived growth factor C.
     
 0.696
Z169_15915
Intersectin-2.
   
 0.696
Your Current Organism:
Egretta garzetta
NCBI taxonomy Id: 188379
Other names: E. garzetta, little egret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.