node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A5C3QF49 | A0A5C3QN18 | A0A5C3QF49 | A0A5C3QN18 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | WD40 repeat-like protein. | 0.709 |
A0A5C3QF49 | A0A5C3QQ62 | A0A5C3QF49 | A0A5C3QQ62 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Gcd10p family-domain-containing protein. | 0.526 |
A0A5C3QF49 | A0A5C3QRX3 | A0A5C3QF49 | A0A5C3QRX3 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Ribosome biogenesis protein tsr1. | 0.595 |
A0A5C3QF49 | A0A5C3QUX4 | A0A5C3QF49 | A0A5C3QUX4 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.828 |
A0A5C3QF49 | ERB1 | A0A5C3QF49 | A0A5C3QHT8 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.892 |
A0A5C3QF49 | NAT10 | A0A5C3QF49 | A0A5C3QAJ1 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | 0.725 |
A0A5C3QF49 | SPB1 | A0A5C3QF49 | A0A5C3R0L5 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. | 0.576 |
A0A5C3QF49 | TRM8 | A0A5C3QF49 | A0A5C3R0V5 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.730 |
A0A5C3QF49 | TRM82 | A0A5C3QF49 | A0A5C3QJH7 | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.466 |
A0A5C3QN18 | A0A5C3QF49 | A0A5C3QN18 | A0A5C3QF49 | WD40 repeat-like protein. | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.709 |
A0A5C3QN18 | A0A5C3QQ62 | A0A5C3QN18 | A0A5C3QQ62 | WD40 repeat-like protein. | Gcd10p family-domain-containing protein. | 0.444 |
A0A5C3QN18 | A0A5C3QRX3 | A0A5C3QN18 | A0A5C3QRX3 | WD40 repeat-like protein. | Ribosome biogenesis protein tsr1. | 0.924 |
A0A5C3QN18 | A0A5C3QUX4 | A0A5C3QN18 | A0A5C3QUX4 | WD40 repeat-like protein. | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.873 |
A0A5C3QN18 | A0A5C3QZY2 | A0A5C3QN18 | A0A5C3QZY2 | WD40 repeat-like protein. | 18S rRNA biogenesis protein. | 0.996 |
A0A5C3QN18 | ERB1 | A0A5C3QN18 | A0A5C3QHT8 | WD40 repeat-like protein. | Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.915 |
A0A5C3QN18 | NAT10 | A0A5C3QN18 | A0A5C3QAJ1 | WD40 repeat-like protein. | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | 0.998 |
A0A5C3QN18 | SPB1 | A0A5C3QN18 | A0A5C3R0L5 | WD40 repeat-like protein. | AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. | 0.952 |
A0A5C3QN18 | TRM8 | A0A5C3QN18 | A0A5C3R0V5 | WD40 repeat-like protein. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.419 |
A0A5C3QN18 | TRM82 | A0A5C3QN18 | A0A5C3QJH7 | WD40 repeat-like protein. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.791 |
A0A5C3QQ62 | A0A5C3QF49 | A0A5C3QQ62 | A0A5C3QF49 | Gcd10p family-domain-containing protein. | S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.526 |