node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMG11467.1 | SMG25963.1 | SAMN03080602_00596 | SAMN03080602_01695 | Dihydrolipoamide dehydrogenase. | DtxR family transcriptional regulator, Mn-dependent transcriptional regulator. | 0.500 |
SMG11467.1 | SMG53161.1 | SAMN03080602_00596 | SAMN03080602_04357 | Dihydrolipoamide dehydrogenase. | Dihydrolipoamide dehydrogenase. | 0.887 |
SMG11467.1 | gcvH | SAMN03080602_00596 | SAMN03080602_00184 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.964 |
SMG11467.1 | thyA | SAMN03080602_00596 | SAMN03080602_02788 | Dihydrolipoamide dehydrogenase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.560 |
SMG13246.1 | SMG25963.1 | SAMN03080602_00765 | SAMN03080602_01695 | Peptidase S24-like; Belongs to the peptidase S26 family. | DtxR family transcriptional regulator, Mn-dependent transcriptional regulator. | 0.708 |
SMG23694.1 | SMG25963.1 | SAMN03080602_01474 | SAMN03080602_01695 | NRAMP (natural resistance-associated macrophage protein) metal ion transporters. | DtxR family transcriptional regulator, Mn-dependent transcriptional regulator. | 0.509 |
SMG25950.1 | SMG25954.1 | SAMN03080602_01693 | SAMN03080602_01694 | Ferrous iron transport protein B. | Ferrous iron transport protein B. | 0.994 |
SMG25950.1 | SMG25963.1 | SAMN03080602_01693 | SAMN03080602_01695 | Ferrous iron transport protein B. | DtxR family transcriptional regulator, Mn-dependent transcriptional regulator. | 0.983 |
SMG25954.1 | SMG25950.1 | SAMN03080602_01694 | SAMN03080602_01693 | Ferrous iron transport protein B. | Ferrous iron transport protein B. | 0.994 |
SMG25954.1 | SMG25963.1 | SAMN03080602_01694 | SAMN03080602_01695 | Ferrous iron transport protein B. | DtxR family transcriptional regulator, Mn-dependent transcriptional regulator. | 0.975 |
SMG25963.1 | SMG11467.1 | SAMN03080602_01695 | SAMN03080602_00596 | DtxR family transcriptional regulator, Mn-dependent transcriptional regulator. | Dihydrolipoamide dehydrogenase. | 0.500 |
SMG25963.1 | SMG13246.1 | SAMN03080602_01695 | SAMN03080602_00765 | DtxR family transcriptional regulator, Mn-dependent transcriptional regulator. | Peptidase S24-like; Belongs to the peptidase S26 family. | 0.708 |
SMG25963.1 | SMG23694.1 | SAMN03080602_01695 | SAMN03080602_01474 | DtxR family transcriptional regulator, Mn-dependent transcriptional regulator. | NRAMP (natural resistance-associated macrophage protein) metal ion transporters. | 0.509 |
SMG25963.1 | SMG25950.1 | SAMN03080602_01695 | SAMN03080602_01693 | DtxR family transcriptional regulator, Mn-dependent transcriptional regulator. | Ferrous iron transport protein B. | 0.983 |
SMG25963.1 | SMG25954.1 | SAMN03080602_01695 | SAMN03080602_01694 | DtxR family transcriptional regulator, Mn-dependent transcriptional regulator. | Ferrous iron transport protein B. | 0.975 |
SMG25963.1 | SMG39206.1 | SAMN03080602_01695 | SAMN03080602_02838 | DtxR family transcriptional regulator, Mn-dependent transcriptional regulator. | Dihydrofolate synthase / folylpolyglutamate synthase. | 0.496 |
SMG25963.1 | SMG44869.1 | SAMN03080602_01695 | SAMN03080602_03371 | DtxR family transcriptional regulator, Mn-dependent transcriptional regulator. | Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. | 0.729 |
SMG25963.1 | SMG53161.1 | SAMN03080602_01695 | SAMN03080602_04357 | DtxR family transcriptional regulator, Mn-dependent transcriptional regulator. | Dihydrolipoamide dehydrogenase. | 0.507 |
SMG25963.1 | gcvH | SAMN03080602_01695 | SAMN03080602_00184 | DtxR family transcriptional regulator, Mn-dependent transcriptional regulator. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.587 |
SMG25963.1 | thyA | SAMN03080602_01695 | SAMN03080602_02788 | DtxR family transcriptional regulator, Mn-dependent transcriptional regulator. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.542 |