STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KOG68502.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)    
Predicted Functional Partners:
KOG68503.1
ATP-dependent protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.990
KOG68533.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.987
priA
Phosphoribosyl isomerase; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family.
  
    0.986
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
       0.984
KOG68534.1
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.984
hisB
Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.984
KOG68506.1
Amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.984
KOG68507.1
Imidazole glycerol phosphate synthase subunit HisH; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.984
KOG68509.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.984
hisF
Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
       0.984
Your Current Organism:
Kitasatospora aureofaciens
NCBI taxonomy Id: 1894
Other names: ATCC 10762, ATCC 23884, BCRC 11610, CBS 434.51, CBS 664.68, CCRC 11610, CCRC:11610, CECT 3206, CIP 57.11, DSM 40127, HAMBI 313, HUT 6048, HUT 6097, ICMP 499, IFO 12594, IFO 12843, IFO 3712, ISP 5127, JCM 4008, JCM 4624, K. aureofaciens, KACC 20180, LMG 5968, LMG:5968, NBRC 12594, NBRC 12843, NBRC 3712, NCAIM B.01479, NCIMB 8234, NRRL 2209, NRRL B-5404, NRRL-ISP 5127, NRRL-ISP:5127, NRRL:B:5404, RIA 57, Streptomyces aureifaciens, Streptomyces aureofaciens, Streptomyces aureofaciens subsp. aureofaciens, VKM Ac-771
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