node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MK0513 | csl4 | MK0513 | MK0060 | Predicted RNA-binding protein containing KH domain). | Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | 0.984 |
MK0513 | mra1 | MK0513 | MK0202 | Predicted RNA-binding protein containing KH domain). | Uncharacterized conserved protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.999 |
MK0513 | rcl1 | MK0513 | MK0001 | Predicted RNA-binding protein containing KH domain). | RNA phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. | 0.984 |
MK0513 | rps1A | MK0513 | MK1461 | Predicted RNA-binding protein containing KH domain). | Ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. | 0.996 |
MK0513 | rps6A | MK0513 | MK1446 | Predicted RNA-binding protein containing KH domain). | Ribosomal protein S6E (S10); Belongs to the eukaryotic ribosomal protein eS6 family. | 0.999 |
MK0513 | rpsD | MK0513 | MK1472 | Predicted RNA-binding protein containing KH domain). | Ribosomal protein related to S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.999 |
MK0513 | rpsK | MK0513 | MK1473 | Predicted RNA-binding protein containing KH domain). | Ribosomal protein S11; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. | 0.999 |
MK0513 | rpsL | MK0513 | MK0681 | Predicted RNA-binding protein containing KH domain). | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. | 0.990 |
MK0513 | sik1 | MK0513 | MK0559 | Predicted RNA-binding protein containing KH domain). | Protein implicated in ribosomal biogenesis, Nop56p homolog. | 0.999 |
MK0513 | tmcA | MK0513 | MK0146 | Predicted RNA-binding protein containing KH domain). | Predicted P-loop ATPase fused to an acetyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.999 |
csl4 | MK0513 | MK0060 | MK0513 | Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Predicted RNA-binding protein containing KH domain). | 0.984 |
csl4 | mra1 | MK0060 | MK0202 | Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Uncharacterized conserved protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.986 |
csl4 | rcl1 | MK0060 | MK0001 | Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | RNA phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. | 0.981 |
csl4 | rps1A | MK0060 | MK1461 | Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family. | 0.845 |
csl4 | rps6A | MK0060 | MK1446 | Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Ribosomal protein S6E (S10); Belongs to the eukaryotic ribosomal protein eS6 family. | 0.963 |
csl4 | rpsD | MK0060 | MK1472 | Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Ribosomal protein related to S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.974 |
csl4 | rpsK | MK0060 | MK1473 | Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Ribosomal protein S11; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. | 0.961 |
csl4 | rpsL | MK0060 | MK0681 | Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. | 0.838 |
csl4 | sik1 | MK0060 | MK0559 | Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Protein implicated in ribosomal biogenesis, Nop56p homolog. | 0.979 |
csl4 | tmcA | MK0060 | MK0146 | Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Predicted P-loop ATPase fused to an acetyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.889 |