STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MK0229Archaea-specific pyridoxal phosphate-dependent enzyme; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (392 aa)    
Predicted Functional Partners:
sepS
Phenylalanyl-tRNA synthetase alpha subunit, archaeal type; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
  
 0.998
MK1100
Predicted extracellular polysaccharide hydrolase of the endo alpha-1,4 polygalactosaminidase family.
     
  0.900
MK1125
Predicted extracellular polysaccharide hydrolase of the Endo alpha-1,4 polygalactosaminidase family; Artificial frameshift.
     
  0.900
MK1187
Predicted extracellular polysaccharide hydrolase of the endo alpha-1,4 polygalactosaminidase family; Artificial frameshift.
     
  0.900
MK0211
Uncharacterized protein conserved in archaea.
    
 
 0.865
spcS
Pyridoxal-phosphate-dependent enzyme related to glutamate decarboxylase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis.
  
   
 0.864
selA
Selenocysteine synthase.
   
  
 0.753
MK0228
Uncharacterized conserved protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).
       0.723
trkA
NAD-binding component of a K+ transport system.
   
    0.668
pheS
Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
  
 
 0.667
Your Current Organism:
Methanopyrus kandleri
NCBI taxonomy Id: 190192
Other names: M. kandleri AV19, Methanopyrus kandleri AV19, Methanopyrus kandleri str. AV19
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