node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MK0077 | nop1 | MK0077 | MK0560 | Predicted GTPase or GTP-binding protein. | Fibrillarin-like rRNA methylase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.687 |
MK0077 | sen2_1 | MK0077 | MK0341 | Predicted GTPase or GTP-binding protein. | tRNA splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | 0.799 |
MK0340 | MK0342 | MK0340 | MK0342 | Predicted Fe-S oxidoreductase. | Predicted transcriptional regulator containing DNA-binding HTH domain. | 0.548 |
MK0340 | MK0344 | MK0340 | MK0344 | Predicted Fe-S oxidoreductase. | Predicted 23S rRNA methylase containing THUMP domain. | 0.487 |
MK0340 | sen2_1 | MK0340 | MK0341 | Predicted Fe-S oxidoreductase. | tRNA splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | 0.585 |
MK0340 | trpS | MK0340 | MK0343 | Predicted Fe-S oxidoreductase. | Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.487 |
MK0342 | MK0340 | MK0342 | MK0340 | Predicted transcriptional regulator containing DNA-binding HTH domain. | Predicted Fe-S oxidoreductase. | 0.548 |
MK0342 | MK0344 | MK0342 | MK0344 | Predicted transcriptional regulator containing DNA-binding HTH domain. | Predicted 23S rRNA methylase containing THUMP domain. | 0.678 |
MK0342 | sen2_1 | MK0342 | MK0341 | Predicted transcriptional regulator containing DNA-binding HTH domain. | tRNA splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | 0.741 |
MK0342 | trpS | MK0342 | MK0343 | Predicted transcriptional regulator containing DNA-binding HTH domain. | Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.678 |
MK0344 | MK0340 | MK0344 | MK0340 | Predicted 23S rRNA methylase containing THUMP domain. | Predicted Fe-S oxidoreductase. | 0.487 |
MK0344 | MK0342 | MK0344 | MK0342 | Predicted 23S rRNA methylase containing THUMP domain. | Predicted transcriptional regulator containing DNA-binding HTH domain. | 0.678 |
MK0344 | sen2_1 | MK0344 | MK0341 | Predicted 23S rRNA methylase containing THUMP domain. | tRNA splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | 0.651 |
MK0344 | trpS | MK0344 | MK0343 | Predicted 23S rRNA methylase containing THUMP domain. | Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.773 |
MK0744 | nop1 | MK0744 | MK0560 | Predicted nuclei-acid-binding protein, consists of a PIN domain and a Zn-ribbon. | Fibrillarin-like rRNA methylase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.470 |
MK0744 | sen2_1 | MK0744 | MK0341 | Predicted nuclei-acid-binding protein, consists of a PIN domain and a Zn-ribbon. | tRNA splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | 0.488 |
cca1 | dnaG | MK1366 | MK0617 | tRNA nucleotidyltransferase (CCA-adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | Predicted bacterial-type DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.622 |
cca1 | sen2_1 | MK1366 | MK0341 | tRNA nucleotidyltransferase (CCA-adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | tRNA splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | 0.486 |
dnaG | cca1 | MK0617 | MK1366 | Predicted bacterial-type DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | tRNA nucleotidyltransferase (CCA-adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | 0.622 |
dnaG | nop1 | MK0617 | MK0560 | Predicted bacterial-type DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Fibrillarin-like rRNA methylase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.522 |