STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MK0541Uncharacterized protein conserved in archaea; DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double- stranded DNA substrates. (242 aa)    
Predicted Functional Partners:
MK1436
Topoisomerase V.
      
 0.879
MK0540
Uncharacterized protein.
       0.737
MK0539
Coenzyme F420-reducing hydrogenase, beta subunit.
       0.608
MK0542
Predicted transcriptional regulator consisting of a V4R domain and a DNA-binding HTH domain.
       0.432
MK0538
Coenzyme F420-reducing hydrogenase, gamma subunit.
       0.410
Your Current Organism:
Methanopyrus kandleri
NCBI taxonomy Id: 190192
Other names: M. kandleri AV19, Methanopyrus kandleri AV19, Methanopyrus kandleri str. AV19
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.