STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nop1Fibrillarin-like rRNA methylase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (232 aa)    
Predicted Functional Partners:
rpsE
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
  
 0.999
mra1
Uncharacterized conserved protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
   
 0.999
MK0513
Predicted RNA-binding protein containing KH domain).
   
 0.999
sik1
Protein implicated in ribosomal biogenesis, Nop56p homolog.
 
 
 0.999
rps6A
Ribosomal protein S6E (S10); Belongs to the eukaryotic ribosomal protein eS6 family.
   
 0.999
rpsD
Ribosomal protein related to S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 0.999
rpsK
Ribosomal protein S11; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
  
 0.999
rpl8A
Ribosomal protein HS6-type (S12/L30/L7a); Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 0.999
rpsI
Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
 
 0.994
MK0045
Predicted GTPase of the YlqF family.
  
 0.976
Your Current Organism:
Methanopyrus kandleri
NCBI taxonomy Id: 190192
Other names: M. kandleri AV19, Methanopyrus kandleri AV19, Methanopyrus kandleri str. AV19
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