STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speAPyruvoyl-dependent arginine decarboxylase; PvlArgDC; Belongs to the PdaD family. (150 aa)    
Predicted Functional Partners:
speB
Agmatinase; Belongs to the arginase family.
 
  
 0.978
nadK
Predicted sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.837
suhB
Myo-inositol-1(or 4)-monophosphatase; Archaea-specific fructose-1,6-bisphosphatase fused to predicted pyrophosphatase of the PRA-PH family.
       0.832
argH
Argininosuccinate lyase.
     
 0.809
dys1
Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
     
 0.727
pyrF
Orotidine-5'-phosphate decarboxylase.
 
   
 0.722
efp
Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
  
 0.705
MK1576
Amino acid transporter.
     
 0.620
MK0736
Uncharacterized protein.
       0.554
hmg1
Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
      
 0.547
Your Current Organism:
Methanopyrus kandleri
NCBI taxonomy Id: 190192
Other names: M. kandleri AV19, Methanopyrus kandleri AV19, Methanopyrus kandleri str. AV19
Server load: low (26%) [HD]