node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MK0407 | cyaB | MK0407 | MK0871 | Uncharacterized protein conserved in archaea. | Adenylate cyclase, class 2 (thermophilic). | 0.566 |
MK0827 | cyaB | MK0827 | MK0871 | Predicted nucleotide kinase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Adenylate cyclase, class 2 (thermophilic). | 0.900 |
MK0827 | ndk | MK0827 | MK1591 | Predicted nucleotide kinase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.990 |
MK0827 | nrdD | MK0827 | MK0901 | Predicted nucleotide kinase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Oxygen-sensitive ribonucleoside-triphosphate reductase. | 0.914 |
MK0870 | cpsB_1 | MK0870 | MK0873 | Uncharacterized protein. | Mannose-6-phosphate isomerase. | 0.476 |
MK0870 | cyaB | MK0870 | MK0871 | Uncharacterized protein. | Adenylate cyclase, class 2 (thermophilic). | 0.773 |
MK0870 | eriC | MK0870 | MK0872 | Uncharacterized protein. | Chloride channel protein EriC. | 0.642 |
cpsB_1 | MK0870 | MK0873 | MK0870 | Mannose-6-phosphate isomerase. | Uncharacterized protein. | 0.476 |
cpsB_1 | cyaB | MK0873 | MK0871 | Mannose-6-phosphate isomerase. | Adenylate cyclase, class 2 (thermophilic). | 0.577 |
cpsB_1 | eriC | MK0873 | MK0872 | Mannose-6-phosphate isomerase. | Chloride channel protein EriC. | 0.588 |
cyaB | MK0407 | MK0871 | MK0407 | Adenylate cyclase, class 2 (thermophilic). | Uncharacterized protein conserved in archaea. | 0.566 |
cyaB | MK0827 | MK0871 | MK0827 | Adenylate cyclase, class 2 (thermophilic). | Predicted nucleotide kinase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | 0.900 |
cyaB | MK0870 | MK0871 | MK0870 | Adenylate cyclase, class 2 (thermophilic). | Uncharacterized protein. | 0.773 |
cyaB | cpsB_1 | MK0871 | MK0873 | Adenylate cyclase, class 2 (thermophilic). | Mannose-6-phosphate isomerase. | 0.577 |
cyaB | dacZ | MK0871 | MK1507 | Adenylate cyclase, class 2 (thermophilic). | Uncharacterized conserved protein; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | 0.514 |
cyaB | eriC | MK0871 | MK0872 | Adenylate cyclase, class 2 (thermophilic). | Chloride channel protein EriC. | 0.653 |
cyaB | moaA | MK0871 | MK1540 | Adenylate cyclase, class 2 (thermophilic). | Molybdenum cofactor biosynthesis enzyme; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | 0.822 |
cyaB | mptA | MK0871 | MK0485 | Adenylate cyclase, class 2 (thermophilic). | Uncharacterized conserved protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.805 |
cyaB | ndk | MK0871 | MK1591 | Adenylate cyclase, class 2 (thermophilic). | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.903 |
cyaB | nrdD | MK0871 | MK0901 | Adenylate cyclase, class 2 (thermophilic). | Oxygen-sensitive ribonucleoside-triphosphate reductase. | 0.900 |