node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argH | fumA | MK0622 | MK0086 | Argininosuccinate lyase. | Fumarate hydratase class I, C-terminal domain. | 0.851 |
argH | mdh | MK0622 | MK1069 | Argininosuccinate lyase. | NADPH-dependent L-malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.887 |
argH | ttdA | MK0622 | MK0085 | Argininosuccinate lyase. | Fumarate hydratase class I, N-terminal domain. | 0.836 |
comC | mdh | MK0392 | MK1069 | L-sulfolactate dehydrogenase. | NADPH-dependent L-malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.948 |
comC | sucD | MK0392 | MK0732 | L-sulfolactate dehydrogenase. | Succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.447 |
fumA | argH | MK0086 | MK0622 | Fumarate hydratase class I, C-terminal domain. | Argininosuccinate lyase. | 0.851 |
fumA | mdh | MK0086 | MK1069 | Fumarate hydratase class I, C-terminal domain. | NADPH-dependent L-malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.985 |
fumA | rplD | MK0086 | MK0414 | Fumarate hydratase class I, C-terminal domain. | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.461 |
fumA | sdhA | MK0086 | MK0828 | Fumarate hydratase class I, C-terminal domain. | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.985 |
fumA | sucC | MK0086 | MK0731 | Fumarate hydratase class I, C-terminal domain. | Succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.769 |
fumA | sucD | MK0086 | MK0732 | Fumarate hydratase class I, C-terminal domain. | Succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.735 |
fumA | ttdA | MK0086 | MK0085 | Fumarate hydratase class I, C-terminal domain. | Fumarate hydratase class I, N-terminal domain. | 0.999 |
gapA | mdh | MK0618 | MK1069 | Glyceraldehyde-3-phosphate dehydrogenase. | NADPH-dependent L-malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.922 |
gapA | rplD | MK0618 | MK0414 | Glyceraldehyde-3-phosphate dehydrogenase. | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.937 |
gapA | sdhA | MK0618 | MK0828 | Glyceraldehyde-3-phosphate dehydrogenase. | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.654 |
gapA | sucC | MK0618 | MK0731 | Glyceraldehyde-3-phosphate dehydrogenase. | Succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.677 |
gapA | sucD | MK0618 | MK0732 | Glyceraldehyde-3-phosphate dehydrogenase. | Succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.647 |
mdh | argH | MK1069 | MK0622 | NADPH-dependent L-malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | Argininosuccinate lyase. | 0.887 |
mdh | comC | MK1069 | MK0392 | NADPH-dependent L-malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | L-sulfolactate dehydrogenase. | 0.948 |
mdh | fumA | MK1069 | MK0086 | NADPH-dependent L-malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | Fumarate hydratase class I, C-terminal domain. | 0.985 |