STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pksG3-hydroxy-3-methylglutaryl CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (350 aa)    
Predicted Functional Partners:
hmg1
Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
 
 0.999
MK1377
Predicted nucleic-acid-binding protein containing a Zn-ribbon.
 
 
 0.999
MK1378
Acetyl-CoA acetyltransferase.
 
 0.999
MK1380
Predicted transcriptional regulator containing a DNA-binding HTH domain.
  
    0.959
porG_1
Pyruvate:ferredoxin oxidoreductase, gamma subunit.
    
 0.921
porB_1
Pyruvate:ferredoxin oxidoreductase, beta subunit.
    
 0.910
porB_2
Pyruvate:ferredoxin oxidoreductase, beta subunit.
    
 0.910
porD
Pyruvate:ferredoxin oxidoreductase, delta subunit.
    
  0.902
porA_1
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
    
  0.902
porA_2
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
    
  0.902
Your Current Organism:
Methanopyrus kandleri
NCBI taxonomy Id: 190192
Other names: M. kandleri AV19, Methanopyrus kandleri AV19, Methanopyrus kandleri str. AV19
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.