STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MK1456Mn2+-dependent serine/threonine protein kinase. (206 aa)    
Predicted Functional Partners:
qri7
Metal-dependent protease with possible chaperone activity; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
   
 0.995
MK0270
Uncharacterized conserved protein.
    
 
 0.983
MK0638
Uncharacterized conserved protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family.
    0.941
rps24A
Ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family.
 
    0.813
hslV_1
Protease subunit of the proteasome; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
   
 0.739
groL
HSP60 family chaperonin; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
 
  
 0.735
MK1453
Uncharacterized protein conserved in archaea; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
 
     0.728
rps31
Ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family.
       0.713
eif2g
Translation elongation factor, GTPase; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
 
   
 0.698
rps6A
Ribosomal protein S6E (S10); Belongs to the eukaryotic ribosomal protein eS6 family.
 
   
 0.693
Your Current Organism:
Methanopyrus kandleri
NCBI taxonomy Id: 190192
Other names: M. kandleri AV19, Methanopyrus kandleri AV19, Methanopyrus kandleri str. AV19
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