node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MK0270 | MK1456 | MK0270 | MK1456 | Uncharacterized conserved protein. | Mn2+-dependent serine/threonine protein kinase. | 0.983 |
MK0270 | groL | MK0270 | MK1006 | Uncharacterized conserved protein. | HSP60 family chaperonin; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family. | 0.542 |
MK0270 | hslV_1 | MK0270 | MK0385 | Uncharacterized conserved protein. | Protease subunit of the proteasome; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.739 |
MK0270 | qri7 | MK0270 | MK1458 | Uncharacterized conserved protein. | Metal-dependent protease with possible chaperone activity; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.983 |
MK0638 | MK1456 | MK0638 | MK1456 | Uncharacterized conserved protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. | Mn2+-dependent serine/threonine protein kinase. | 0.941 |
MK0638 | eif2g | MK0638 | MK1447 | Uncharacterized conserved protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. | Translation elongation factor, GTPase; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.475 |
MK0638 | rps24A | MK0638 | MK1454 | Uncharacterized conserved protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. | Ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.417 |
MK1453 | MK1456 | MK1453 | MK1456 | Uncharacterized protein conserved in archaea; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | Mn2+-dependent serine/threonine protein kinase. | 0.728 |
MK1453 | eif2g | MK1453 | MK1447 | Uncharacterized protein conserved in archaea; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | Translation elongation factor, GTPase; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.649 |
MK1453 | rps24A | MK1453 | MK1454 | Uncharacterized protein conserved in archaea; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | Ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.967 |
MK1453 | rps31 | MK1453 | MK1455 | Uncharacterized protein conserved in archaea; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | Ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.890 |
MK1453 | rps6A | MK1453 | MK1446 | Uncharacterized protein conserved in archaea; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | Ribosomal protein S6E (S10); Belongs to the eukaryotic ribosomal protein eS6 family. | 0.836 |
MK1456 | MK0270 | MK1456 | MK0270 | Mn2+-dependent serine/threonine protein kinase. | Uncharacterized conserved protein. | 0.983 |
MK1456 | MK0638 | MK1456 | MK0638 | Mn2+-dependent serine/threonine protein kinase. | Uncharacterized conserved protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. | 0.941 |
MK1456 | MK1453 | MK1456 | MK1453 | Mn2+-dependent serine/threonine protein kinase. | Uncharacterized protein conserved in archaea; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.728 |
MK1456 | eif2g | MK1456 | MK1447 | Mn2+-dependent serine/threonine protein kinase. | Translation elongation factor, GTPase; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.698 |
MK1456 | groL | MK1456 | MK1006 | Mn2+-dependent serine/threonine protein kinase. | HSP60 family chaperonin; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family. | 0.735 |
MK1456 | hslV_1 | MK1456 | MK0385 | Mn2+-dependent serine/threonine protein kinase. | Protease subunit of the proteasome; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.739 |
MK1456 | qri7 | MK1456 | MK1458 | Mn2+-dependent serine/threonine protein kinase. | Metal-dependent protease with possible chaperone activity; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.995 |
MK1456 | rps24A | MK1456 | MK1454 | Mn2+-dependent serine/threonine protein kinase. | Ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.813 |