STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (329 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.992
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
 
 0.988
FN0644
Uroporphyrin-III C-methyltransferase; uroporphyrinogen-III synthase.
 
  
 0.976
gltX
Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
     
 0.926
FN0460
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.860
FN0642
Hypothetical protein.
       0.581
FN0643
Hypothetical DNA-binding protein.
       0.581
FN0641
Methyltransferase.
       0.570
FN0539
Precorrin-2 oxidase; Ferrochelatase.
 
   
 0.532
FN0647
Transcriptional regulator.
       0.527
Your Current Organism:
Fusobacterium nucleatum ATCC 25586
NCBI taxonomy Id: 190304
Other names: F. nucleatum subsp. nucleatum ATCC 25586, Fusobacterium nucleatum subsp. nucleatum ATCC 25586, Fusobacterium nucleatum subsp. nucleatum JCM 8532, Fusobacterium nucleatum subsp. nucleatum str. ATCC 25586, Fusobacterium nucleatum subsp. nucleatum strain ATCC 25586
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