node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
XCC0018 | XCC0019 | XCC0018 | XCC0019 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.734 |
XCC0018 | serA | XCC0018 | XCC0020 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | D-3-phosphoglycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.678 |
XCC0019 | XCC0018 | XCC0019 | XCC0018 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.734 |
XCC0019 | serA | XCC0019 | XCC0020 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | D-3-phosphoglycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.785 |
XCC0384 | serA | XCC0384 | XCC0020 | Oxidoreductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | D-3-phosphoglycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.575 |
XCC0747 | gpm | XCC0747 | XCC2712 | Phosphoglycerate mutase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | 0.950 |
XCC0747 | serA | XCC0747 | XCC0020 | Phosphoglycerate mutase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | D-3-phosphoglycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.907 |
XCC0747 | serA-2 | XCC0747 | XCC1825 | Phosphoglycerate mutase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | D-3-phosphoglycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.907 |
glyA | metL | XCC0690 | XCC1800 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.637 |
glyA | serA | XCC0690 | XCC0020 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | D-3-phosphoglycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.859 |
glyA | serA-2 | XCC0690 | XCC1825 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | D-3-phosphoglycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.859 |
glyA | serC | XCC0690 | XCC1589 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.639 |
gpm | XCC0747 | XCC2712 | XCC0747 | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | Phosphoglycerate mutase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.950 |
gpm | serA | XCC2712 | XCC0020 | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | D-3-phosphoglycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.907 |
gpm | serA-2 | XCC2712 | XCC1825 | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | D-3-phosphoglycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.918 |
metL | glyA | XCC1800 | XCC0690 | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.637 |
metL | serA | XCC1800 | XCC0020 | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | D-3-phosphoglycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.800 |
metL | serA-2 | XCC1800 | XCC1825 | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | D-3-phosphoglycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.823 |
metL | serC | XCC1800 | XCC1589 | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.622 |
nodQ | serA | XCC3171 | XCC0020 | ATP sulfurylase/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | D-3-phosphoglycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.605 |