node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
XCC0126 | XCC1547 | XCC0126 | XCC1547 | Deoxycytidylate deaminase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 5'-nucleotidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.900 |
XCC0126 | dut | XCC0126 | XCC3858 | Deoxycytidylate deaminase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.945 |
XCC0126 | surE | XCC0126 | XCC1706 | Deoxycytidylate deaminase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
XCC0126 | tdk | XCC0126 | XCC4143 | Deoxycytidylate deaminase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Thymidine kinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.932 |
XCC0126 | thyA | XCC0126 | XCC0787 | Deoxycytidylate deaminase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.940 |
XCC0126 | tmk | XCC0126 | XCC3931 | Deoxycytidylate deaminase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.934 |
XCC1547 | XCC0126 | XCC1547 | XCC0126 | 5'-nucleotidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Deoxycytidylate deaminase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.900 |
XCC1547 | dut | XCC1547 | XCC3858 | 5'-nucleotidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
XCC1547 | surE | XCC1547 | XCC1706 | 5'-nucleotidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
XCC1547 | tdk | XCC1547 | XCC4143 | 5'-nucleotidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Thymidine kinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.900 |
XCC1547 | thyA | XCC1547 | XCC0787 | 5'-nucleotidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.900 |
XCC1547 | tmk | XCC1547 | XCC3931 | 5'-nucleotidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.900 |
dcd | dut | XCC2570 | XCC3858 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.927 |
dcd | folA | XCC2570 | XCC0788 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Dihydrofolate reductase type III; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.417 |
dcd | ndk | XCC2570 | XCC1981 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.926 |
dfp | dut | XCC3859 | XCC3858 | DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.929 |
dut | XCC0126 | XCC3858 | XCC0126 | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Deoxycytidylate deaminase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.945 |
dut | XCC1547 | XCC3858 | XCC1547 | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 5'-nucleotidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.900 |
dut | dcd | XCC3858 | XCC2570 | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.927 |
dut | dfp | XCC3858 | XCC3859 | dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.929 |