STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ligADNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (783 aa)    
Predicted Functional Partners:
CC_3610
DNA ligase, ATP-dependent, putative; Identified by match to protein family HMM.
    
 0.981
CC_0043
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.882
CC_1528
DNA helicase II; Identified by match to protein family HMM.
 
  
 0.878
leuS
leucyl-tRNA synthetase; Identified by match to TIGR protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 
 0.819
CC_1523
Exonuclease; Identified by match to PFAM protein family HMM PF00929.
     
 0.803
CC_1524
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
CC_2505
Identified by match to protein family HMM; Belongs to the glutaredoxin family. Monothiol subfamily.
     
 0.742
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family.
 
   
 0.686
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
   
 0.594
HolA
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.579
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.