node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CC_1553 | CC_1889 | CC_1553 | CC_1889 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleotide reductase-related protein; Similar to GP:3402271; identified by sequence similarity; putative. | 0.903 |
CC_1553 | CC_2051 | CC_1553 | CC_2051 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Pyruvate kinase; Identified by match to protein family HMM; Belongs to the pyruvate kinase family. | 0.918 |
CC_1553 | CC_3492 | CC_1553 | CC_3492 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.902 |
CC_1553 | gmk | CC_1553 | CC_1681 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.923 |
CC_1553 | ndk | CC_1553 | CC_1699 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.931 |
CC_1553 | rpoZ | CC_1553 | CC_1552 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.747 |
CC_1680 | gmk | CC_1680 | CC_1681 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.966 |
CC_1680 | rpoZ | CC_1680 | CC_1552 | Conserved hypothetical protein; Identified by Glimmer2; putative. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.531 |
CC_1889 | CC_1553 | CC_1889 | CC_1553 | Ribonucleotide reductase-related protein; Similar to GP:3402271; identified by sequence similarity; putative. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.903 |
CC_1889 | CC_2051 | CC_1889 | CC_2051 | Ribonucleotide reductase-related protein; Similar to GP:3402271; identified by sequence similarity; putative. | Pyruvate kinase; Identified by match to protein family HMM; Belongs to the pyruvate kinase family. | 0.906 |
CC_1889 | CC_3492 | CC_1889 | CC_3492 | Ribonucleotide reductase-related protein; Similar to GP:3402271; identified by sequence similarity; putative. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.901 |
CC_1889 | gmk | CC_1889 | CC_1681 | Ribonucleotide reductase-related protein; Similar to GP:3402271; identified by sequence similarity; putative. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.910 |
CC_1889 | guaA | CC_1889 | CC_1620 | Ribonucleotide reductase-related protein; Similar to GP:3402271; identified by sequence similarity; putative. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.527 |
CC_1889 | ndk | CC_1889 | CC_1699 | Ribonucleotide reductase-related protein; Similar to GP:3402271; identified by sequence similarity; putative. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.914 |
CC_2051 | CC_1553 | CC_2051 | CC_1553 | Pyruvate kinase; Identified by match to protein family HMM; Belongs to the pyruvate kinase family. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.918 |
CC_2051 | CC_1889 | CC_2051 | CC_1889 | Pyruvate kinase; Identified by match to protein family HMM; Belongs to the pyruvate kinase family. | Ribonucleotide reductase-related protein; Similar to GP:3402271; identified by sequence similarity; putative. | 0.906 |
CC_2051 | CC_3492 | CC_2051 | CC_3492 | Pyruvate kinase; Identified by match to protein family HMM; Belongs to the pyruvate kinase family. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.906 |
CC_2051 | gmk | CC_2051 | CC_1681 | Pyruvate kinase; Identified by match to protein family HMM; Belongs to the pyruvate kinase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.922 |
CC_2051 | guaA | CC_2051 | CC_1620 | Pyruvate kinase; Identified by match to protein family HMM; Belongs to the pyruvate kinase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.501 |
CC_2051 | ndk | CC_2051 | CC_1699 | Pyruvate kinase; Identified by match to protein family HMM; Belongs to the pyruvate kinase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.910 |