STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackA2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (402 aa)    
Predicted Functional Partners:
pta2
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
pta1
Catalyzes the formation of acetyl phosphate from acetyl-CoA and phosphate; can also act with other short-chain acyl-CoAs; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
maeB
Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.989
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.976
xfp
Phosphoketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.961
prpE
Catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.955
AIB12972.1
2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.930
AIB13178.1
GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.881
AIB11068.1
acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.869
aceA
Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.850
Your Current Organism:
Azospirillum brasilense
NCBI taxonomy Id: 192
Other names: A. brasilense, ATCC 29145, Azospirillum brasiliense, LMG 13127, LMG:13127, NBRC 102289, NRRL B-14647, Roseomonas fauriae, Spirillum lipoferum, bacterium ASAZOES-148, strain sp. 7
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.