node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIB12972.1 | AIB13178.1 | ABAZ39_13480 | ABAZ39_14530 | 2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.988 |
AIB12972.1 | ackA2 | ABAZ39_13480 | ABAZ39_02625 | 2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.930 |
AIB12972.1 | acsA | ABAZ39_13480 | ABAZ39_12800 | 2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.906 |
AIB12972.1 | citE | ABAZ39_13480 | ABAZ39_12345 | 2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | malyl-CoA thiolesterase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. | 0.886 |
AIB12972.1 | gabD | ABAZ39_13480 | ABAZ39_05595 | 2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Succinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.864 |
AIB12972.1 | gltA | ABAZ39_13480 | ABAZ39_08140 | 2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.890 |
AIB12972.1 | maeB | ABAZ39_13480 | ABAZ39_00120 | 2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
AIB12972.1 | mls | ABAZ39_13480 | ABAZ39_01350 | 2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. | 0.743 |
AIB12972.1 | prpE | ABAZ39_13480 | ABAZ39_09210 | 2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.867 |
AIB12972.1 | pta2 | ABAZ39_13480 | ABAZ39_02620 | 2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.975 |
AIB13178.1 | AIB12972.1 | ABAZ39_14530 | ABAZ39_13480 | GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.988 |
AIB13178.1 | ackA2 | ABAZ39_14530 | ABAZ39_02625 | GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.881 |
AIB13178.1 | acsA | ABAZ39_14530 | ABAZ39_12800 | GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.835 |
AIB13178.1 | citE | ABAZ39_14530 | ABAZ39_12345 | GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | malyl-CoA thiolesterase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. | 0.489 |
AIB13178.1 | gabD | ABAZ39_14530 | ABAZ39_05595 | GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Succinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.803 |
AIB13178.1 | gltA | ABAZ39_14530 | ABAZ39_08140 | GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.838 |
AIB13178.1 | maeB | ABAZ39_14530 | ABAZ39_00120 | GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
AIB13178.1 | mls | ABAZ39_14530 | ABAZ39_01350 | GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. | 0.741 |
AIB13178.1 | prpE | ABAZ39_14530 | ABAZ39_09210 | GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.865 |
AIB13178.1 | pta2 | ABAZ39_14530 | ABAZ39_02620 | GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.980 |